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Dinner / Parmesan Meatloaf: The Ultimate Recipe for a Delicious Dinner

Parmesan Meatloaf: The Ultimate Recipe for a Delicious Dinner

July 11, 2025 by NancyDinner

Parmesan Meatloaf: Prepare to rediscover a classic comfort food, elevated to new heights! Forget everything you thought you knew about meatloaf – this isn’t your grandma’s dry, bland version. We’re talking about a moist, flavorful, and utterly irresistible dish that will have everyone begging for seconds. This recipe is so good, it might just become your new weeknight staple.

Meatloaf, in its essence, is a testament to resourceful cooking. Its origins can be traced back to medieval Europe, where cooks sought to utilize every scrap of meat. Over time, it evolved into a beloved dish in American households, particularly during the Great Depression, as a way to stretch limited resources. While the basic concept remains the same, the possibilities for flavor variations are endless.

What makes this Parmesan Meatloaf so special? It’s the perfect balance of savory meat, aromatic herbs, and the nutty, salty goodness of Parmesan cheese. The Parmesan not only adds incredible flavor but also helps to create a beautiful, slightly crispy crust. People adore meatloaf because it’s hearty, satisfying, and relatively easy to prepare. Plus, it’s fantastic for meal prepping – leftovers make amazing sandwiches! Get ready to experience a meatloaf that’s anything but ordinary.

Parmesan Meatloaf this Recipe

Ingredients:

  • 2 pounds ground beef (80/20 blend is ideal for flavor and moisture)
  • 1 cup grated Parmesan cheese, divided (reserve ¼ cup for topping)
  • 1 cup breadcrumbs (plain or Italian seasoned, your preference!)
  • 1 medium onion, finely chopped
  • 2 cloves garlic, minced
  • 1 red bell pepper, finely diced
  • 1/2 cup milk (whole milk adds richness)
  • 2 large eggs, lightly beaten
  • 2 tablespoons Worcestershire sauce
  • 1 tablespoon Dijon mustard
  • 1 teaspoon dried oregano
  • 1 teaspoon dried basil
  • 1/2 teaspoon salt (or to taste)
  • 1/4 teaspoon black pepper (or to taste)
  • 1/2 cup ketchup (for topping)
  • 2 tablespoons brown sugar (for topping, optional but adds a nice sweetness)
  • 1 tablespoon apple cider vinegar (for topping, balances the sweetness)

Preparing the Meatloaf Mixture:

  1. First, let’s get our vegetables prepped. Finely chop the onion and mince the garlic. Dicing the red bell pepper into small pieces is also important – we don’t want huge chunks in our meatloaf. I like to use a food processor for the onion and bell pepper to get them really fine, but chopping by hand works just as well.
  2. Now, in a large bowl, combine the ground beef, ¾ cup of the grated Parmesan cheese (remember to save that ¼ cup for the topping!), breadcrumbs, chopped onion, minced garlic, and diced red bell pepper. Make sure everything is evenly distributed.
  3. In a separate, smaller bowl, whisk together the milk, beaten eggs, Worcestershire sauce, Dijon mustard, dried oregano, dried basil, salt, and pepper. This wet mixture will help bind everything together and add moisture to the meatloaf.
  4. Pour the wet mixture over the ground beef mixture in the large bowl. Using your hands (yes, it’s the best way!), gently mix everything together until just combined. Be careful not to overmix! Overmixing can result in a tough meatloaf. We want it to be tender and juicy.
  5. Once everything is combined, give it a taste! You can cook a tiny bit in a pan to check the seasoning. Adjust the salt and pepper as needed to your liking. Remember, the Parmesan cheese is already salty, so be mindful of that.

Shaping and Preparing for Baking:

  1. Preheat your oven to 350°F (175°C). This temperature allows the meatloaf to cook evenly without drying out too quickly.
  2. Lightly grease a loaf pan (9×5 inch is a good size) with cooking spray or a little bit of oil. This will prevent the meatloaf from sticking to the pan. You can also line the pan with parchment paper, leaving an overhang on the sides, for easy removal after baking.
  3. Gently transfer the meatloaf mixture into the prepared loaf pan. Use your hands to shape it into an even loaf, pressing down lightly to ensure it fills the pan completely.
  4. Now, for the topping! In a small bowl, whisk together the ketchup, brown sugar (if using), and apple cider vinegar. This glaze will add a delicious sweet and tangy flavor to the meatloaf.
  5. Spread the ketchup mixture evenly over the top of the meatloaf. Then, sprinkle the remaining ¼ cup of grated Parmesan cheese over the ketchup glaze. The Parmesan will melt and create a beautiful, cheesy crust.

Baking the Parmesan Meatloaf:

  1. Place the loaf pan in the preheated oven and bake for 60-75 minutes, or until the internal temperature reaches 160°F (71°C). Use a meat thermometer inserted into the center of the meatloaf to check for doneness.
  2. During baking, you might notice some fat rendering out of the meatloaf. This is perfectly normal. If you want to reduce the amount of fat, you can carefully drain it off halfway through the baking time. Just tilt the loaf pan and spoon out the excess fat.
  3. If the top of the meatloaf starts to brown too quickly, you can loosely tent it with aluminum foil for the last 15-20 minutes of baking. This will prevent it from burning.
  4. Once the meatloaf is cooked through and the internal temperature reaches 160°F (71°C), remove it from the oven and let it rest for at least 10-15 minutes before slicing and serving. This resting period allows the juices to redistribute throughout the meatloaf, resulting in a more tender and flavorful dish.

Serving Suggestions:

  1. After the meatloaf has rested, carefully slice it into thick or thin slices, depending on your preference. If you lined the pan with parchment paper, you can easily lift the meatloaf out of the pan using the overhang.
  2. Serve the Parmesan Meatloaf hot with your favorite side dishes. Mashed potatoes, roasted vegetables, green beans, and a simple salad are all great options.
  3. Leftover meatloaf can be stored in an airtight container in the refrigerator for up to 3-4 days. It’s also freezer-friendly! Wrap individual slices tightly in plastic wrap and then place them in a freezer bag. Frozen meatloaf can be reheated in the oven, microwave, or skillet.
  4. Pro Tip: For extra flavor, try adding a layer of cooked bacon to the top of the meatloaf before baking. The bacon will add a smoky, salty flavor that complements the Parmesan cheese perfectly.
  5. Another Tip: You can also customize the meatloaf by adding different vegetables or spices. Try adding chopped mushrooms, carrots, or spinach to the mixture. Or, experiment with different herbs and spices, such as Italian seasoning, garlic powder, or onion powder.
  6. For a healthier version: Use ground turkey or chicken instead of ground beef. You can also substitute whole wheat breadcrumbs for regular breadcrumbs.
  7. To make it gluten-free: Use gluten-free breadcrumbs or almond flour instead of regular breadcrumbs.

Parmesan Meatloaf

Conclusion:

This isn’t your grandma’s meatloaf – unless your grandma was secretly a culinary genius hiding a love for Italian flavors! Seriously, this Parmesan Meatloaf is a game-changer. The combination of savory ground meat, aromatic herbs, and that salty, nutty Parmesan cheese creates a flavor explosion that will have everyone at the table asking for seconds. It’s moist, it’s flavorful, and it’s surprisingly easy to make, making it a weeknight dinner champion.

But why is this recipe a must-try? Beyond the incredible taste, it’s the versatility. You can easily adapt it to your own preferences and dietary needs. Looking for a lighter option? Substitute ground turkey or chicken for the beef. Want to add a little kick? Throw in a pinch of red pepper flakes or a dash of your favorite hot sauce. Need to make it gluten-free? Simply swap out the breadcrumbs for gluten-free alternatives like crushed rice crackers or almond flour. The possibilities are endless!

And let’s talk serving suggestions. While this Parmesan Meatloaf is delicious on its own, it truly shines when paired with the right accompaniments. I personally love serving it with a side of creamy mashed potatoes and roasted asparagus. The richness of the meatloaf is perfectly balanced by the lightness of the vegetables. Another fantastic option is to slice it up and serve it on toasted ciabatta bread with a smear of pesto and a sprinkle of fresh mozzarella. Talk about a gourmet sandwich! For a more Italian-inspired meal, try serving it with a side of spaghetti tossed in a simple marinara sauce. The flavors complement each other beautifully.

Don’t be afraid to get creative in the kitchen! This recipe is a blank canvas for your culinary imagination. Experiment with different herbs, cheeses, and vegetables to create your own signature version of this classic dish. You could try adding sun-dried tomatoes and olives for a Mediterranean twist, or incorporating sautéed mushrooms and onions for a more earthy flavor.

I know you might be thinking, “Meatloaf? Really?” But trust me on this one. This Parmesan Meatloaf is not your average meatloaf. It’s a flavor-packed, crowd-pleasing dish that will quickly become a family favorite. It’s the perfect comfort food for a chilly evening, and it’s also elegant enough to serve to guests. Plus, it’s a great way to use up any leftover breadcrumbs or Parmesan cheese you might have lying around.

So, what are you waiting for? Grab your ingredients, preheat your oven, and get ready to experience the best meatloaf you’ve ever tasted. I’m confident that you’ll love this recipe as much as I do. And when you do, please, please, please share your experience with me! I’d love to hear what you think, what variations you tried, and how much your family enjoyed it. Leave a comment below, tag me on social media, or send me an email. I’m always eager to hear from my readers and see their culinary creations. Happy cooking! I can’t wait to see your amazing Parmesan Meatloaf creations!


Parmesan Meatloaf: The Ultimate Recipe for a Delicious Dinner

Classic meatloaf elevated with Parmesan cheese! This juicy and flavorful meatloaf features a cheesy crust and a sweet and tangy ketchup glaze. Perfect for a comforting family meal.

Prep Time20 minutes
Cook Time60 minutes
Total Time80 minutes
Category: Dinner
Yield: 6-8 servings
Save This Recipe

Ingredients

  • 2 pounds ground beef (80/20 blend)
  • 1 cup grated Parmesan cheese, divided (reserve ¼ cup for topping)
  • 1 cup breadcrumbs (plain or Italian seasoned)
  • 1 medium onion, finely chopped
  • 2 cloves garlic, minced
  • 1 red bell pepper, finely diced
  • 1/2 cup milk (whole milk)
  • 2 large eggs, lightly beaten
  • 2 tablespoons Worcestershire sauce
  • 1 tablespoon Dijon mustard
  • 1 teaspoon dried oregano
  • 1 teaspoon dried basil
  • 1/2 teaspoon salt (or to taste)
  • 1/4 teaspoon black pepper (or to taste)
  • 1/2 cup ketchup (for topping)
  • 2 tablespoons brown sugar (for topping, optional)
  • 1 tablespoon apple cider vinegar (for topping)
  • Cooking spray or oil, for greasing the pan

Instructions

  1. Prepare Vegetables: Finely chop the onion and mince the garlic. Dice the red bell pepper into small pieces.
  2. Combine Meatloaf Mixture: In a large bowl, combine ground beef, ¾ cup Parmesan cheese, breadcrumbs, chopped onion, minced garlic, and diced red bell pepper.
  3. Prepare Wet Mixture: In a separate bowl, whisk together milk, beaten eggs, Worcestershire sauce, Dijon mustard, dried oregano, dried basil, salt, and pepper.
  4. Combine Wet and Dry: Pour the wet mixture over the ground beef mixture. Gently mix with your hands until just combined. Do not overmix.
  5. Taste and Adjust: Cook a tiny bit in a pan to check the seasoning. Adjust the salt and pepper as needed.
  6. Preheat Oven: Preheat oven to 350°F (175°C).
  7. Prepare Loaf Pan: Lightly grease a 9×5 inch loaf pan with cooking spray or oil. You can also line the pan with parchment paper.
  8. Shape Meatloaf: Gently transfer the meatloaf mixture into the prepared loaf pan. Shape it into an even loaf.
  9. Prepare Topping: In a small bowl, whisk together ketchup, brown sugar (if using), and apple cider vinegar.
  10. Add Topping: Spread the ketchup mixture evenly over the top of the meatloaf. Sprinkle the remaining ¼ cup of grated Parmesan cheese over the ketchup glaze.
  11. Bake: Place the loaf pan in the preheated oven and bake for 60-75 minutes, or until the internal temperature reaches 160°F (71°C).
  12. Drain Fat (Optional): If desired, carefully drain off any excess fat halfway through the baking time.
  13. Tent with Foil (Optional): If the top of the meatloaf starts to brown too quickly, loosely tent it with aluminum foil for the last 15-20 minutes of baking.
  14. Rest: Once cooked, remove from oven and let rest for 10-15 minutes before slicing.
  15. Slice and Serve: Slice into thick or thin slices and serve hot with your favorite side dishes.

Notes

  • Don’t Overmix: Overmixing the meatloaf mixture will result in a tough meatloaf.
  • Internal Temperature: Ensure the meatloaf reaches an internal temperature of 160°F (71°C) for food safety.
  • Resting Time: Allowing the meatloaf to rest before slicing is crucial for a more tender and flavorful result.
  • Customization: Feel free to add other vegetables, spices, or a layer of bacon to customize the meatloaf to your liking.
  • Healthier Version: Use ground turkey or chicken and whole wheat breadcrumbs for a healthier option.
  • Gluten-Free: Use gluten-free breadcrumbs or almond flour for a gluten-free version.
  • Storage: Leftover meatloaf can be stored in an airtight container in the refrigerator for up to 3-4 days or frozen for longer storage.

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